GeneAb™

Desmin

(In the pipeline)

Select Format:

Select Volume:

Price:

$105.00

Quantity:

Cat. No.

IHC561-100

Inquire

Description

Desmin is a type III intermediate filament present in normal smooth, skeletal, and cardiac muscle cells. Analysis by light microscopy suggests desmin localizes towards the periphery of Z-lines in striated muscle fibrils. Desmin connects cytoplasmic dense bodies to membranous dense plaques in smooth muscles. Anti-Desmin stains rhabdomyomas, leiomyosarcoma, rhabdomyosarcoma, leiomyomas, and perivascular cells from skin glomus tumors, and is used to identify the myogenic characteristics of tumors. Desmin can also be found in myofibroblasts and desmoid fibromatosis.

Specifications

Clone IHC561
Source Mouse Monoclonal
Positive Control Skeletal Muscle
Dilution Range 1:100 - 1:200

References

  1. Nadji M, et al. Immunoperoxidase Techniques ASCP. 1986.
  2. Altmannsberger M, et al. Am J Pathol. 1985; 118:85-95.
  3. Debus E, et al. EMBO J. 1983; 2:2305-12.
  4. Attanoos RL, et al. Histopathology. 2003; 43:231-8.
  5. Chu PG, et al. Mod Pathol. 2001; 14:465-71.
  6. Gill SA, et al. Acta Cytol. 2000: 44:976-80.