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Description

E-cadherin is an intercellular adhesion molecule present in epithelial cells. Anti-E-cadherin stains glandular epithelium, as well as lung, gastrointestinal and ovarian adenocarcinomas. A panel of antibodies against E-cadherin and p120 is also used to differentiate ductal (membranous staining) and lobular breast cancer (cytoplasmic staining). Anti-E-cadherin also stains some thyroid cancers.

• References

  1. Han AC, et al. Hum Pathol. 1997; 28:641-5.
  2. Simsir A, et al. Diagn Cytopathol. 1999; 20:125-30.
  3. Lear MP, et al. Histopathology. 1998; 32:209-16.
  4. Karayiannakis AG, et al. Hepatogastroenterology. 1998; 45:2437-42.
  5. Peralta Soler A, et al. Hum Pathol. 1997; 28:734-9.
  6. Abutaily AS, et al. J Clin Pathol. 2002; 55:662-8.
  7. Wahed A, et al. Ann Diagn Pathol. 2002; 6:349-51.
  8. Acs G, et al. Am J Clin Pathol. 2001; 115:85-98.
  9. Dabbs DJ, et al. Am J Surg Pathol. 2007; 31:427-37.

Specifications

Literature