GeneAb™

ERCC1

(In the pipeline)

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$190.00

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Cat. No.

IHC568-100

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Description

Excision Repair Cross Complementing 1 (ERCC1) is a DNA repair enzyme involved in the repair of UV-induced DNA damage. ERCC1 overexpression is associated with tumor progression in many malignancies such as ovarian cancer, head squamous cell carcinoma, non-small cell lung cancer (NSCLC), and esophageal cancer.

Specifications

Clone IHC568
Source Mouse Monoclonal
Positive Control Prostate, Prostate Carcinoma
Dilution Range 1:100 - 1:200

References

  1. Park CH, et al. J Biol Chem. 1995; 270:22657-60.
  2. van Duin M, et al. Cell. 1986; 44:913-23.
  3. Lee KH, et al. Lung Cancer. 2008; 60:401-7.
  4. Dabholkar M, et al. J Clin Invest. 1994; 94:703-8.
  5. Handra-Luca A, et al. Clin Cancer Res. 2007; 13:3855-9.
  6. Joshi MB, et al. Clin Cancer Res. 2005; 11:2215-21.
  7. Olaussen KA, et al. N Engl J Med. 2006; 355:983–91.