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GeneAb™ Ep-CAM/Epithelial Specific Antigen Antibody
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Designations
IVD:
RUO:
Reference Panels
Breast/Gynecological Pathology
Dermatopathology
Gastrointestinal (GI) Pathology
Genitourinary (GU) Pathology
Head and Neck Pathology
Hematopathology
Neuropathology
Pediatric Pathology
Pulmonary Pathology
Soft Tissue Pathology
Cytopathology
GeneAb™
Ep-CAM/Epithelial Specific Antigen
(In the pipeline)
Select Format:
Concentrate
Predilute
Positive Control Slides
Select Volume:
0.1 ml
1 ml
7 ml
25 ml
3 slides/package
Price:
$125.00
Quantity:
Cat. No.
IHC567-100
Inquire
Description
Epithelial Cell Adhesion Molecule (EpCAM) is a transmembrane glycoprotein that mediates cell–cell adhesion in epithelia. It is normally present on most baso-lateral surfaces of normal epithelial cells and is absent in myoepithelial cells, hepatocytes, adult squamous epithelia, mesothelial cells, and fibroblasts. Anti-EpCAM stains most adenocarcinomas and neuroendocrine tumors, including small cell carcinomas. A minority of renal clear cell carcinoma, renal oncocytoma, and hepatocellular carcinoma stain positively for EpCAM, while Anti-EpCAM stains nearly all basal cell carcinoma. Anti-EpCAM stains chromophobe renal cell carcinoma, papillary renal cell carcinoma, and cholangiocarcinoma more frequently. Anti-EpCAM can be useful for distinguishing malignancy in the peritoneal and pleural cavities.
References
Schnell U, et al. 2013; 1828:1989-2001.
Latza, et al. J Clin Pathol. 1990; 43:213-19.
Ma CK, et al. Am J Clin Pathol. 1993; 99:551-7.
Ordóñez NG. Mod Pathol. 2006; 19:417-28.
Tope WD, et al. Dermatol Surg. 2000; 26:415-8.
Ordóñez NG. Adv Anat Pathol. 2006; 13:16-25.
Ordóñez NG. Am J Clin Pathol. 1998; 109:85-9.
Specifications
Clone
IHC567
Source
Mouse Monoclonal
Positive Control
Colon Adenocarcinoma
Dilution Range
1:100 - 1:400
Literature
Catalog
Data Sheet
SDS Sheet
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