GeneAb™

Factor XIIIa

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$130.00

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Cat. No.

IHC572-100

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Description

Factor XIIIa (FXIIIa), also known as activated Factor XIII, is a blood coagulation factor that stabilizes fibrin and is present in monocytes, macrophages, platelets, megakaryocytes, dermal dendritic cells, and fibroblast-like mesenchymal or histiocytic cells in the placenta. Anti-Factor XIIIa is useful for distinguishing between dermatofibrosarcoma protuberans (±), dermatofibroma (mostly +), and desmoplastic malignant melanoma (-). Hemangioendothelioma, hemangiopericytoma, capillary hemagioblastoma, hepatocellular carcinoma, glomus tumor, xanthogranuloma, xanthoma, and meningioma all stain positively with Anti-Factor XIIIa.

Specifications

Clone IHC572
Source Mouse Monoclonal
Positive Control Dermatofibroma
Dilution Range 1:100 - 1:200

References

  1. Abenoza P, et al. Am J Dermatopathol. 1993; 15:429-34.
  2. Horenstein MG, et al. Am J Surg Pathol. 2000; 24:996-1003.
  3. Kraus MD, et al. Am J Dermatopathol. 2001; 23:104-11.