Fascin is an actin cross-linking protein associated with cell motility. Fascin is detectable in dendritic cells, Reed Sternberg cells, nodular sclerosis variants, mixed cellularity, and lymphocyte depletion in Hodgkin’s disease, while being undetectable in lymphoid cells, plasma cells, and myeloid cells. Anti-Fascin is useful for differentiating between Hodgkin’s and non-Hodgkin’s lymphoma. As Fascin is absent in neoplastic follicles in follicular lymphoma, Anti-Fascin is useful for differentiating these lymphomas from reactive follicular hyperplasia where the number of follicular dendritic cells are normal or increased.

• IHC573-Fascin Datasheet-IVD

• MSDS

CLONE:
IHC573

ISOTYPE:


HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Hodgkin’s lymphoma, tonsil

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVD