Flt-1/VEGFR1 (In the pipeline)
FLT-1, also known as Fms Related Tyrosine Kinase 1 or VEGFR1 (vascular endothelial growth factor receptor 1), is a tyrosine kinase involved in lymphangiogenesis, angiogenesis, and wound healing. It is present in endothelial cells, osteoblasts, placental trophoblasts, renal mesangial cells, and some hematopoietic stem cells. Anti-FLT-1/VEGFR1 is useful for identifying carcinomas of the larynx and esophagus.
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- Zhou X, et al. Sci Rep. 2015; 5:10071.
- Xu WW, et al. Oncotarget. 2015; 6:1790-805.