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Description

Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament protein that is present in astrocytes and some ependymal cells of the central nervous system. In the peripheral nervous system, GFAP is present in Schwann cells, enteric glial cells, and satellite cells. Anti-GFAP staining is useful in differentiating neoplasms of astrocyte origin from other neoplasms in the central nervous system.

• References

  1. Isaacs A, et al. Genomics. 1998; 51:152–4.
  2. Jacque CM, et al. J Neurol Sci. 1987; 35:147–55.
  3. Roessmann U, et al. Brain Res. 1980; 200:13–21.
  4. Korshunov AG, et al. Arkh Patol. 1995; 57:30-8.
  5. McLendon RE, et al. Brain Pathol. 1994; 4:221-8.

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Literature