GeneAb™

Granzyme B

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$135.00

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Cat. No.

IHC588-100

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Description

Granzyme B is a serine protease present in the granules of cytotoxic T-cells and natural killer (NK) cells. Anti-Granzyme B is useful for recognizing NK cell, anaplastic large cell, or T-cell lymphomas. Granzyme B is also present in Reed-Sternberg cells of Hodgkin's disease.

Specifications

Clone IHC588
Source Mouse Monoclonal
Positive Control Spleen, Anaplastic Large Cell Lymphoma
Dilution Range 1:100 - 1:200

References

  1. Oudejans JJ, et al. Blood. 1997; 89:1376-82.
  2. Oudejans JJ, et al. Am J Pathol. 1996; 148:233-40.
  3. Liu J, et al. J Dermatol. 2003; 30:735-41.
  4. Kato N, et al. Am J Dermatopathol. 2003; 25:142-7.
  5. Kummer JA, et al. Clin Exp Immunol. 1995; 100:164-72.