GeneAb™ HGAL [IHC598] on Tonsil
hGAL

CAT. NO. IHC598
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Description

Human Germinal center-Associated Lymphoma (HGAL) protein, also known as Germinal Center-associated Lymphoma Protein or GCET, is expressed specically in the cytoplasm of germinal center B-cells. As HGAL is absent in mantle and marginal zone B-cells, and in the interfollicular and paracortical regions of normal tonsils and lymph nodes, this protein is an optimal prognostic marker for B cell lymphomas derived from germinal centers, as well as follicular lymphoma. HGAL expression is also indicative of a subset of Hodgkin’s lymphoma of germinal center derivation and improved survival, and predicts the outcome in patients with diuse large B-cell lymphoma.

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Specifications

CLONE:
IHC598

ISOTYPE:


HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil, Lymph node

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVD


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