GeneAb™

HER2/neu

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$60.00

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Cat. No.

IHC042-100

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Description

The Her2/Neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number of carcinomas. Overexpression of the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between Her2 and p53 has also been documented, as overexpression of both proteins has been associated with early invasion and metastasis in bladder cancer.
  • References
    1. Suthipintawong C, et al. Diagn Cytopathol. 1997; 17:127-33.
    2. Alexiev BA, et al. Gen Diagn Pathol. 1997; 142:271-9.
    3. Fernández Aceñero MJ, et al. Gen Diagn Pathol. 1997; 142:289-96.
    4. Koeppen HKW, et al. Histopathology. 2001; 38:96-104.
    5. Moch H, et al. Virchows Arch A Pathol Anat Histopathol. 1993; 423:329-34.
    6. Cetin B, et al. Transl Gastroenterol Hepatol. 2016; 1:59.

Specifications

Clone IHC042
Source Mouse Monoclonal
Positive Control Breast Carcinoma
Dilution Range 1:50-1:200

Literature