GeneAb™

HER2/neu

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$145.00

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Cat. No.

IHC002-100

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Description

The Her2/Neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number of carcinomas. Overexpression of the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between Her2 and p53 has also been documented, as overexpression of both proteins has been associated with early invasion and metastasis in bladder cancer.

Specifications

Clone IHC002
Source Mouse Monoclonal
Positive Control Breast Carcinoma
Dilution Range 1:100 - 1:200

References

  1. Suthipintawong C, et al. Diagn Cytopathol. 1997; 17:127-33.
  2. Alexiev BA, et al. Gen Diagn Pathol. 1997; 142:271-9.
  3. Fernández Aceñero MJ, et al. Gen Diagn Pathol. 1997; 142:289-96.
  4. Koeppen HKW, et al. Histopathology. 2001; 38:96-104.
  5. Moch H, et al. Virchows Arch A Pathol Anat Histopathol. 1993; 423:329-34.
  6. Cetin B, et al. Transl Gastroenterol Hepatol. 2016; 1:59.