Human Placental Lactogen (hPL) (In the pipeline)
Human placental lactogen, also known as hPL or human chorionic somatomammotropin, is a placental hormone responsible for regulating the metabolism of the mother during pregnancy, to ensure adequate energy supply to the fetus. hPL is clinically indicated in choriocarcinoma, being expressed in the syncytiotrophoblastic cells, and has also been associated with a rare variant of trophoblastic tumors reported in the testis. This rare variant had resembled uterine placental site trophoblastic tumors, and consisted entirely of intermediate trophoblasts which were diffusely positive for human placental lactogen.
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- Josimovich JB, et al. Endocrinology. 2006; 358:773-84.
- Shih IM, et al. Am J Surg Pathol. 2004; 28:1177-83.
- Ulbright TM, et al. Am J Surg Pathol. 1997; 21:282-88.