GeneAb™

Inhibin Alpha

(In the pipeline)

Select Format:

Select Volume:

Price:

$155.00

Quantity:

Cat. No.

IHC607-100

Inquire

Description

Inhibin Alpha, also known as INHA, is a peptide hormone belonging to the transforming growth factor-beta (TGF-beta) family. It is produced by ovarian granulosa cells in female follicles and by Sertoli cells in the male seminiferous tubules, with the purpose of inhibiting the release of follicle-stimulating hormone, and is also found in the prostate, brain, and adrenal glands. This marker has proven effective in aiding with a number of differential diagnoses, including distinguishing between adrenal cortical tumors and renal cell carcinoma, and between intrauterine and ectopic pregnancy in endometrial curettage. Anti-Inhibin Alpha can also be used to detect for sex cord stromal tumors of the ovary as well as trophoblastic tumors.
  • References
    1. Kommoss F, et al. Mod Pathol. 1998; 11:656-64.
    2. Fetsch PA, et al. Cancer. 1999; 87:168-72.
    3. McCluggage WG. Histopathology. 2002; 40:309-26.
    4. Arora DS, et al. J Pathol. 1997; 181:413-8.
    5. McCluggage WG, et al. Am J Surg Pathol. 1998; 22:615-9.
    6. Matias-Guiu X, et al. Hum Pathol. 1998; 29:840-5.
    7. Pelkey TJ, et al. Hum Pathol. 1999; 30:26-31.
    8. Stewart CJ, et al. Histopathology. 1997; 31:67-74.
    9. Yamashita K, et al. Am J Obstet Gynecol. 1997; 177:1450-7.
    10. Groome NG, et al. Hybridoma. 1990; 9:31-42.
    11. Iczkowski KA, et al. Mod Pathol. 1998; 11:774-9.
    12. Groome NG, et al. Hybridoma. 1991; 10:309-16.

Specifications

Clone IHC607
Source Mouse Monoclonal
Positive Control Adrenal Cortex
Dilution Range 1:100 - 1:400

Literature