Inhibin Alpha

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Inhibin Alpha, also known as INHA, is a peptide hormone belonging to the transforming growth factor-beta (TGF-beta) family. It is produced by ovarian granulosa cells in female follicles and by Sertoli cells in the male seminiferous tubules, with the purpose of inhibiting the release of follicle-stimulating hormone, and is also found in the prostate, brain, and adrenal glands. This marker has proven effective in aiding with a number of differential diagnoses, including distinguishing between adrenal cortical tumors and renal cell carcinoma, and between intrauterine and ectopic pregnancy in endometrial curettage. Anti-Inhibin Alpha can also be used to detect for sex cord stromal tumors of the ovary as well as trophoblastic tumors.
  • References
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    7. Pelkey TJ, et al. Hum Pathol. 1999; 30:26-31.
    8. Stewart CJ, et al. Histopathology. 1997; 31:67-74.
    9. Yamashita K, et al. Am J Obstet Gynecol. 1997; 177:1450-7.
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    11. Iczkowski KA, et al. Mod Pathol. 1998; 11:774-9.
    12. Groome NG, et al. Hybridoma. 1991; 10:309-16.


Clone IHC607
Source Mouse Monoclonal
Positive Control Adrenal Cortex
Dilution Range 1:50-1:200