GeneAb™

Inhibin Alpha

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$155.00

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Cat. No.

IHC607-100

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Description

Inhibin Alpha, also known as INHA, is a peptide hormone belonging to the transforming growth factor-beta (TGF-beta) family. It is produced by ovarian granulosa cells in female follicles and by Sertoli cells in the male seminiferous tubules, with the purpose of inhibiting the release of follicle-stimulating hormone, and is also found in the prostate, brain, and adrenal glands. This marker has proven effective in aiding with a number of differential diagnoses, including distinguishing between adrenal cortical tumors and renal cell carcinoma, and between intrauterine and ectopic pregnancy in endometrial curettage. Anti-Inhibin Alpha can also be used to detect for sex cord stromal tumors of the ovary as well as trophoblastic tumors.

Specifications

Clone IHC607
Source Mouse Monoclonal
Positive Control Adrenal Cortex
Dilution Range 1:100 - 1:200

References

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  5. McCluggage WG, et al. Am J Surg Pathol. 1998; 22:615-9.
  6. Matias-Guiu X, et al. Hum Pathol. 1998; 29:840-5.
  7. Pelkey TJ, et al. Hum Pathol. 1999; 30:26-31.
  8. Stewart CJ, et al. Histopathology. 1997; 31:67-74.
  9. Yamashita K, et al. Am J Obstet Gynecol. 1997; 177:1450-7.
  10. Groome NG, et al. Hybridoma. 1990; 9:31-42.
  11. Iczkowski KA, et al. Mod Pathol. 1998; 11:774-9.
  12. Groome NG, et al. Hybridoma. 1991; 10:309-16.