GeneAb^TM Ki-67 [IHC067] on Cervical Cancer - 10X

GeneAb^TM Ki-67 [IHC067] on Cervical Cancer - 20X

GeneAb^TM Ki-67 [IHC067] on Cervical Cancer - 40X

Reference Panels

Breast/Gynecological Pathology

Dermatopathology

Gastrointestinal (GI) Pathology

Genitourinary (GU) Pathology

Head and Neck Pathology

Hematopathology

Neuropathology

Pediatric Pathology

Pulmonary Pathology

Soft Tissue Pathology

Cytopathology

GeneAb™

Description

Ki-67 is a nuclear, non-histone protein that is expressed only during active phases of the cell cycle (G1, S, G2 and M), but not in the resting phases (G0 and G1 early phase). Although the antigen has also been associated with ribosomal RNA transcription, it is strongly linked to cell proliferation and has thus been indicated as an effective marker in grading the proliferation rate of tumors, including those of the brain, breast, cervix, and prostate.

• References

  1. Mckeever P, et al. J Neuropathol Exp Neurol. 1998; 57:931-6.
  2. Coons SW, et al. Neurosurgery. 1997; 41:878-84.
  3. Allegra CJ, et al. J Clin Oncol. 2003; 21:241-50.
  4. Pathmanathan N, et al. J Clin Pathol. 2013; 66:512-6.
  5. Jansen R, et al. Br J Cancer. 1998; 78:460-65.
  6. Goodson WH, et al. Breast Cancer Res Treat. 1998; 49:155-164.
  7. Rossi S, et al. Am J Clin Pathol. 2005; 124:295-302.
  8. Pena LL, et al. J Vet Diag Invest. 1998; 10:237-46.
  9. Gibbons D, et al. Comparison Mod Pathol. 1997; 10:409-13.

Specifications

Literature