MMP-9(In the pipeline)
Matrix Metalloproteinase-9 (MMP-9), also known as 92-kDa type IV collagenase or gelatinase B, is a member of a family of proteins involved in degradation of the extracellular matrix (ECM). MMP-9 is produced by neutrophils, macrophages, mast cells, and stromal cells, after activation in inflammatory tissues, and it has been reported that the protein may have a crucial role in angiogenesis and neovascularization. As degradation of collagen IV in the basement membrane and ECM promotes tumor progression, including invasion, metastasis, growth and angiogenesis, MMP-9 is involved in the development of several human malignancies. Overexpression of MMP-9 has been reported in a number of different cancers, including those of the breast and colon, as well as gastric and nasopharyngeal cancers.
|Positive Control||Breast Carcinoma, Placenta|
|Dilution Range||1:100 - 1:200|