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Myeloperoxidase (MPO) is a peroxidase enzyme found most amply in neutrophil granulocytes. Myeloperoxidase is readily detectable in myeloblasts and immature myeloid cells of acute myelogenous leukemia, progranulocytic leukemia, monomyelocytic leukemia, erythroleukemia, myeloblastomas, and other hematopoietic disorders. Anti-Myeloperoxidase has been utilized for immunophenotyping acute lymphoblastic leukemia in bone marrow biopsies, as part of a panel of antibodies. Anti-Myeloperoxidase staining is also used to aid in the diagnosis of extramedullary leukemia or chloroma.
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    11. Kojima M, et al. APMIS. 2003; 111:1133-6.


Clone IHC629
Source Mouse Monoclonal
Positive Control Bone Marrow
Dilution Range 1:50-1:200