GeneAb™

Progesterone Receptor

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$200.00

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Cat. No.

IHC651-100

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Description

Progesterone Receptor (PR), also known as NR3C3 (nuclear receptor subfamily 3, group C, member 3), is an intracellular steroid receptor which mediates the physiological effects of progesterone, a female sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis. Progesterone receptor expression has been linked to the prediction of prognosis in breast cancer, as well as associated responses to endocrine therapy. The progesterone receptor has also been linked to risk for ovarian cancer.

Specifications

Clone IHC651
Source Mouse Monoclonal
Positive Control Breast, Breast Carcinoma
Dilution Range 1:100 - 1:200

References

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  2. Qiu J, et al. Am J Clin Pathol. 2010; 134:813-9.
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  6. Bevitt D, et al. J Pathol. 1997; 183:228-32.
  7. Kell DL, et al. Appl Immunohistochem. 1993; 1:275-81.
  8. Leong ASY, et al. Appl Immunohistochem. 1993; 1:282-8.
  9. Tesch M, et al. Am J Clin Pathol. 1993; 99:8-12.
  10. Clarke CL, et al. Endocrinology. 1987; 121:1123-32.
  11. Feil PD, et al. Endocrinology. 1998; 123:2506-13.