GeneAb™

Podoplanin

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Cat. No.

IHC650-100

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Description

Podoplanin is a transmembrane mucoprotein specifically expressed in the endothelium of lymphatic capillaries, while remaining absent from the blood vasculature. The protein is co-localized with VEGFR3/FLT4 in normal skin and kidney. Anti-Podoplanin is useful in the identification of lymphangiomas, Kaposi’s sarcomas, epithelioid mesotheliomas, hemangioblastomas, seminomas, and some angiosarcomas which likely have lymphatic differentiation.

Specifications

Clone IHC650
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200

References

  1. Ordonez NG. Adv Anat Pathol. 2006; 13:83-8.
  2. Ordonez NG. Hum Pathol. 2005; 36:372-80.
  3. Niakosari F, et al. Arch Dermatol. 2005; 141:440-4.
  4. Galambos C, et al. Pediatr Dev Pathol. 2005; 8:191-9.
  5. Fukunaga M. Histopathology. 2005; 46:396-402.
  6. Fogt F, et al. Oncol Rep. 2004; 11:47-50.
  7. Kahn HJ, et al. Mod Pathol. 2002; 15:434-40.
  8. Franke FE, et al. J Cutan Pathol. 2004; 31:362-7.
  9. Kalof AN,et al. Adv Anat Pathol. 2009; 16:62-4.
  10. Chu AY, et al. Mod Pathol. 2005; 18:105-10.
  11. Iczkowski KA, et al. Hum Pathol. 2008; 39:275–81.