GeneAb™

Podoplanin

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$85.00

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Cat. No.

IHC650-100

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Description

Podoplanin is a transmembrane mucoprotein specifically expressed in the endothelium of lymphatic capillaries, while remaining absent from the blood vasculature. The protein is co-localized with VEGFR3/FLT4 in normal skin and kidney. Anti-Podoplanin is useful in the identification of lymphangiomas, Kaposi’s sarcomas, epithelioid mesotheliomas, hemangioblastomas, seminomas, and some angiosarcomas which likely have lymphatic differentiation.
  • References
    1. Ordonez NG. Adv Anat Pathol. 2006; 13:83-8.
    2. Ordonez NG. Hum Pathol. 2005; 36:372-80.
    3. Niakosari F, et al. Arch Dermatol. 2005; 141:440-4.
    4. Galambos C, et al. Pediatr Dev Pathol. 2005; 8:191-9.
    5. Fukunaga M. Histopathology. 2005; 46:396-402.
    6. Fogt F, et al. Oncol Rep. 2004; 11:47-50.
    7. Kahn HJ, et al. Mod Pathol. 2002; 15:434-40.
    8. Franke FE, et al. J Cutan Pathol. 2004; 31:362-7.
    9. Kalof AN,et al. Adv Anat Pathol. 2009; 16:62-4.
    10. Chu AY, et al. Mod Pathol. 2005; 18:105-10.
    11. Iczkowski KA, et al. Hum Pathol. 2008; 39:275–81.

Specifications

Clone IHC650
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:400

Literature