Prostate Cocktail

(In the pipeline)

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Prostate Cocktail is a combination of Cytokeratin 1, Cytokeratin 5, Cytokeratin 10, Cytokeratin 14, and p63. These four high molecular weight cytokeratins are found in basal epithelia of the prostate gland. p63 is a tumor suppressor protein found in basal epithelial nuclei of the normal prostate, while being negative in malignant tumors associated with the prostate gland, and is therefore useful in differentiating between benign and malignant prostate lesions.
  • References
    1. Signoretti S, et al. Am J Pathol. 2000; 157:1769-75.
    2. Tacha DE, et al. Appl Immunohistochem Mol Morphol. 2004; 12:75-8.
    3. Beach R, et al. Am J Surg Pathol. 2002; 26:1588-96.
    4. Luo J, et al. Cancer Res. 2002; 62:2220-6.
    5. Wang Y, et al. Differentiation. 2001; 68:270-9.
    6. Tokar EJ, et al. Differentiation. 2005; 73:463-73.
    7. Collins AT, et al. J Cell Sci. 2001; 114:3865-72.
    8. Moll R, et al. Cell. 1982; 31:11-24.
    9. Yang Y, et al. Am J Pathol. 1997; 150:693-704.
    10. Yang A, et al. Mol Cell. 1998; 2:305-16.


Clone IHC653
Source Mouse Monoclonal
Positive Control Prostate
Dilution Range 1:50-1:200