(In the pipeline)

Select Format:

Select Volume:




Cat. No.




S100 Calcium Binding Protein P (S100P) is a protein belonging to the S100 family, which function in extracellular and intracellular regulation of a number of cellular processes, including cell cycle progression and differentiation. S100P is expressed in a variety of tissues, including placenta, bladder, spleen, gastric and intestinal mucosa, and is a useful marker for breast, colon, prostate, pancreatic, and lung carcinomas. S100P has been reported as a potential predictor of distant metastasis and poor survival in non-small cell lung carcinomas. Anti-S100P is utilized in detection of adenocarcinomas of the pancreatic and bile ducts, as well as intraductal papillary mucinous neoplasms, including perineural, lymphatic, and minimal invasion. When used as part of a panel, Anti-S100P can be helpful in distinguishing adenocarcinoma from reactive epithelial changes on challenging bile duct biopsies. S100P may be used to help distinguish urothelial carcinomas from other genitourinary neoplasms.
  • References
    1. Esheba GE, et al. Am J Surg Pathol. 2009; 33:347-53.
    2. Chuang AY, et al. Am J Surg Pathol. 2007; 31:1246-55.
    3. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-80.
    4. Gibadulinova A, et al. Amino Acids. 2011; 41:885-92.
    5. Lin F, et al. Am J Surg Pathol. 2008; 32:78-91.
    6. Deng HB, et al. Am J Clin Pathol. 2008; 129:81-8.
    7. Crnogorac-Jurcevic T, et al. J Pathol. 2003; 201:63-74.
    8. Nakata K, et al. Hum Pathol. 2010; 41:824-31.
    9. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-80.
    10. Levy M, et al. Hum Pathol. 2010; 41:1210-9.
    11. Becker T, et al. Eur J Biochem. 1992; 207:541-7 .
    12. Parkkila S, et al. BMC Clin Pathol. 2008; 8:2.
    13. Argumugam T, et al. Clin Cancer Res. 2005; 11:5356-64.
    14. Ohuchida K, et al. Clin Cancer Res. 2006; 12:5411-6.


Clone IHC658
Source Mouse Monoclonal
Positive Control Pancreatic Ductal Adenocarcinoma, Urothelial Carcinoma, Placenta
Dilution Range 1:50-1:200