GeneAb™

SLC10A1

(In the pipeline)

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$210.00

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Cat. No.

IHC662-100

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Description

Solute Carrier family 10 member 1 (SLC10A1), also known as the Na+-Taurocholate Cotransporting Polypeptide (NTCP), is an integral membrane glycoprotein mainly expressed in the liver. Anti-SLC10A1 can be useful for detecting Hepatitis B and D viruses (HBV and HDV), since this transporter is involved in enterohepatic circulation of bile salts as well as cellular entry of HBV and HDV. The SLC10A1 IVD antibody is a diagnostic tool that aids the detection of mutations in the SLC10A1 gene, which have been linked to increased risk of chronic infection with HBV and in turn elevates the risk for developing liver cirrhosis and hepatocellular carcinoma.

Specifications

Clone IHC662
Source Mouse Monoclonal
Positive Control Liver
Dilution Range 1:100 - 1:200

References

  1. Yang J, et al. BMC Cancer. 2016; 16:211.
  2. Watashi K, et al. Int J Mol Sci. 2014; 15:2892-905.
  3. Vaz FM, et al. Dig Dis. 2017; 35:259-60.
  4. Deng M, et al. Exp Ther Med. 2016; 12:3294-300.