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SOX 2, also known as SRY (sex determining region Y)-box 2, is a transcription factor that acts to regulate pluripotency of undifferentiated embryonic stem cells, and to regulate gene expression in the stomach. This diagnostic grade SOX 2 IVD antibody is used to detect melanoma, testicular germ cell tumor, cervical carcinoma, lung cancer, breast cancer with basal cell phenotype, and teratoma of the central nervous system. SOX 2 has been reported as a predictor of poor outcome in stage I lung adenocarcinomas. Anti-SOX 2 is also used to recognize squamous cell carcinomas of the lung and gastrointestinal tract, and may be useful for detecting embryonal carcinoma.
  • References
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Clone IHC665
Source Mouse Monoclonal
Positive Control Lung Squamous Carcinoma
Dilution Range 1:100 - 1:400