T-cell-restricted Intracellular Antigen-1 (TIA1) is an RNA-binding protein involved in apoptosis, which is present in natural killer cells and cytotoxic T cells. Anti-TIA1 stains hairy cell leukemia, large granular lymphocyte (LGL) leukemia, and T-cell lymphoma. As overexpression of TIA1 is characteristic of LGL leukemia and decreased levels of TIA1 is indicative of T-cell lymphocytosis and other T-cell diseases, Anti-TIA1 may be useful in distinguishing between these conditions. TIA1 could also be a useful marker for identifying tumour-infiltrating lymphocytes and understanding the immune response to cancers.

• IHC675-TIA1 Datasheet-IVD

• MSDS

CLONE:
IHC675

ISOTYPE:


HOST SPECIES:
Mouse

CLONALITY:
Monoclonal

POSITIVE CONTROL:
Tonsil

DILUTION RANGE:


INTENDED USE/REG. STATUS:
IVD