GeneAb™

TIM3

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$210.00

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Cat. No.

IHC003-100

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Description

T-cell Immunoglobulin and Mucin-Domain-Containing Molecule-3 (TIM3) is present on T-helper type 1 lymphocytes and other immune cells including dendritic cells and natural killer cells. TIM3 is overexpressed in CD4+ tumor-infiltrating lymphocytes, including those with non-small cell lung cancer associated with poor prognoses. TIM3 has recently emerged as a potential target for cancer immunotherapy.

Specifications

Clone IHC003
Source Mouse Monoclonal
Positive Control Tonsil
Dilution Range 1:100 - 1:200

References

  1. Monney L, et al. Nature. 2002; 415:536-41.
  2. Sánchez-Fueyo A, et al. Nat Immunol. 2003; 4:1093-101.
  3. Anderson AC. Cancer Immun Res. 2014; 2:393–8.
  4. Gao X, et al. PLoS One. 2012; 7:e30676.