GeneAb™

TLE1

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$175.00

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Cat. No.

IHC676-100

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Description

Transducin-Like Enhancer of Split 1 (TLE1) is involved in regulation of neuronal, hematopoiesis, and terminal epithelial differentiation. Nuclear staining of TLE1 has been noted in synovial sarcoma, and TLE1 is rarely detected in soft tissue tumors such as peripheral nerve sheath tumors and pleomorphic sarcoma. Anti-TLE1 is more sensitive and is specific for synovial sarcoma in comparison to other markers such as Bcl2, epithelial membrane antigen, and cytokeratins, and is therefore useful in the diagnosis of synovial sarcoma.

Specifications

Clone IHC676
Source Mouse Monoclonal
Positive Control Synovial Sarcoma
Dilution Range 1:100 - 1:200

References

  1. Jagdis A, et al. Am J Surg Pathol. 2009; 33:1743-51.