GeneAb™

TdT

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$150.00

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Cat. No.

IHC671-100

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Description

Terminal deoxynucleotidyl transferase (TdT) is a DNA polymerase present in normal and malignant pre-B and pre-T cells during early differentiation. Anti-TdT stains nearly all acute lymphoblastic lymphoma/leukemia (ALL) cases, but does not stain pre-B-cell ALL or mature B- and T-cells. Anti-TdT staining is also useful for identifying Type AB thymoma and some chronic myeloid leukemia.

Specifications

Clone IHC671
Source Mouse Monoclonal
Positive Control Thymus
Dilution Range 1:100 - 1:200

References

  1. Stauchen JA, et al. Int J Surg Pathol. 2003; 11:21-4.
  2. Orazi A, et al. Mod Pathol. 1994; 7:582-6.
  3. Suzumija J, et al. J Pathol. 1997; 182:86-91.
  4. Lucas DR, et al. Am J Clin Pathol. 2001; 115:11-7.
  5. Ozdemirli M, et al. Mod Pathol. 2001; 14:1175-82.
  6. Soslow RA, et al. Hum Pathol. 1997; 28:1158-65.
  7. Wang Z, et al. Int J Clin Exp Pathol. 2014; 7:8700-5.
  8. Arber DA, et al. Am J Clin Pathol. 1996; 106:462-8.